Anti-aging and anti-wrinkle skin care treatment from an online doctor or NP. Request wrinkle prescription, prescription retinoid, prescription tretinoin, wrinkle treatment. Upfront pricing. No appointment or insurance needed.
Anti-aging and anti-wrinkle skin care treatment from an online doctor or NP. Request wrinkle prescription, prescription retinoid, prescription tretinoin, wrinkle treatment. Upfront pricing. No appointment or insurance needed. 4.9 426
Ages 18-64
This is right for you if
You want to reduce fine lines and wrinkles
You want more youthful-looking skin
You’re not pregnant or nursing

What's included

Personalized anti-aging and anti-wrinkle treatment plans may include prescription medications like tretinoin (Retin-A) cream that are clinically proven to reduce the appearance of fine lines and wrinkles. Your clinician may also recommend over-the-counter retinol treatments and skin care strategies. You can message your clinician with follow-up questions for 14 days after you get your treatment plan.
Concerned about more than skin treatments?
Commonly prescribed medications
  • Tretinoin (Retin-A, Retin-A Micro, Avita, Atralin, Renova)
  • Tazarotene (Tazorac, Avage)
Compare clinics
This chart is for informational purposes only. Your clinician will determine treatment plans, prescriptions, and number of refills (if any) based on your symptoms and health history.
Anti-aging and anti-wrinkle skin care treatment isn’t available from Curai Health or Wheel at this time. Alpha and SteadyMD have licensed clinicians (like MDs, DOs, and NPs). At Alpha, the typical prescription is a 30- to 90-day supply and 3 to 11 refills. At SteadyMD, the typical prescription is a 30-day supply and 3 refills.

What you’ll need

2 photos: one of your entire face (if applicable), and a close-up of the area you’re most concerned about
A photo ID, like a driver's license or passport, if we need additional identity verification
5 to 10 minutes to answer questions about your symptoms and health history

How it works

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Choose an online clinic
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Fill out an intake form
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Connect with a clinician, no appointment needed
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Get a personalized treatment plan
You can message your clinician with follow-up questions for 14 days after you get your treatment plan.
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You should know
Based on your health information, your clinician may recommend that you see a healthcare provider in person. If that happens, you won’t be charged for your visit. Amazon Clinic doesn’t accept insurance at this time, and isn’t intended for beneficiaries of government payor programs, including Medicare and Medicaid.

Frequently asked questions

What's wrong with aging naturally?
There's nothing wrong with aging naturally. But there's a difference between chronological aging, which is what happens naturally to our cells between birthdays, and photoaging, which is caused by exposure to ultraviolet (UV) radiation from the sun.

Over time, sun exposure can cause skin to wrinkle, thicken, develop hyperpigmented age spots (dark spots), and lose elasticity. How much photoaging you experience depends on your skin phototype and how much time you spend in the sun.

If you're over 30 years old, have a light or medium skin tone that sunburns easily (skin phototypes I to III), and you've spent a lot of time outside without broad-spectrum sunscreen protection, then you're likely to see the effects of photoaging on your skin. If this bothers you, there are a number of clinically proven anti-aging and anti-wrinkle prescription medications and over-the-counter (OTC) ingredients that can help undo some of this sun damage.
What are the best anti-aging treatments and anti-wrinkle treatments?
Prescription medications

The Federal Drug Administration (FDA) has approved several prescription medications that are clinically proven to slow or reverse some of the effects of photoaging. These anti-aging creams, serums, lotions, and gels are called topical retinoids. Retinoids are synthetic and naturally occurring forms of retinol (vitamin A) that are about 10 times more potent than retinol. Topical retinoids and retinol can have similar anti-aging effects on the skin by boosting skin cell turnover, but retinoids tend to work much faster because they're prescription-strength. These drugs are:
• Tazarotene
• Tretinoin (retinoic acid)
Over-the-counter (OTC) treatments

Countless companies promote the anti-aging properties of their cosmetic products. But because face lotions and serums aren't technically drugs, these claims aren't regulated by the FDA. Informally known as cosmeceuticals, many of these drugstore products contain active ingredients that clinical research has shown to reduce fine lines and wrinkles, boost skin elasticity, and even out skin tone. Here are some of the more vetted ingredients you can look for on cosmeceutical labels:
• Alpha hydroxy acids (AHAs) like glycolic acid, lactic acid, and citric acid
• Alpha-lipoic acid
• Azelaic acid
• Bakuchiol, a plant-based retinol alternative (phytoretinol)
• Beta hydroxy acids (BHAs) like salicylic acid
• Ceramides
• Coenzyme Q10
• Collagen peptides
• Ferulic acid
• Hyaluronic acid
• Melatonin
• Nicotinamide, also known as niacinamide, a form of vitamin B3
• Polyphenols and flavonoids (plant compounds) like coffee berry/caffeine, grape seed, green tea, Ginkgo biloba, and ginseng
• Retinol, retinaldehyde, and retinyl esters like retinyl palmitate
• Soybean derivatives, which are rich in flavonoids and amino acids
• Vitamin C (L-ascorbic acid)
• Vitamin E (alpha-tocopherol)
In general, vitamins, polyphenols, and flavonoids are considered antioxidants that work by neutralizing the free radicals that cause oxidative stress in our bodies. Retinols and peptides are considered cell regulators that work by influencing collagen production.

Other therapies and procedures

The following cosmetic therapies and procedures can also reduce the signs of photoaging in skin, although they tend to be more expensive and invasive:
• Botulinum toxin injection (Botox Cosmetic, Daxxify)
• Chemical peel
• Face lift (rhytidectomy)
• Laser resurfacing
• Photodynamic therapy (PDT)
• Skin or dermal fillers (soft tissue injections)
How long does it take tretinoin (Retin-A) to work?
You may see improvement after about 4 weeks of tretinoin (Retin-A) treatment, but it usually takes about 3 to 6 months before you'll see the full effects on your skin.
How can I protect my skin from the effects of aging?
How your skin ages is largely determined by your genes and your skin phototype. For example, people with darker skin tones (phototypes V and VI) might start seeing the effects of photoaging 10 or 20 years after their peers with lighter skin.

But sun exposure, smoking, and air pollution can all accelerate the natural aging process. Can you delay aging? Research shows that it's possible to prolong a youthful appearance by taking the following steps:
• Eat a healthy diet, loaded with antioxidant-rich foods like colorful fruits and vegetables
• Stay hydrated
• Keep your face moisturized
• Avoid tanning beds and prolonged sun exposure
• Wear broad-spectrum sunscreen (SPF 30 or above) every day, even when you're not in direct sunlight (yes, even indoors)
• Don't smoke—it damages skin cells
• Get plenty of sleep
Remember that your skin's appearance tends to be a reflection of your overall health, and health starts from the inside. No matter how old your face looks, it's beautiful, because it's a testament to the life you've lived.
What prescription anti-aging or anti-wrinkle treatments can I get through Amazon Clinic?
Your clinician may prescribe a retinoid like tretinoin (Retin-A, Retin-A Micro, Avita, Atralin, Renova), adapalene (Differin), or tazarotene (Tazorac, Avage). Initial therapies will be those demonstrated to cause fewer adverse skin reactions.

Please note: This information is for general reference only. Your clinician will review your symptoms and health history to determine which (if any) anti-aging and anti-wrinkle treatments are medically appropriate.
How much is Retin-A?
It's unlikely that health insurance will cover the cost of medications like tretinoin (Retin-A) when prescribed as anti-aging and anti-wrinkle skin care treatments. A tube of Retin-A may have an out-of-pocket cost of $12 to $50.
Can I get treatment for spider veins or varicose veins through Amazon Clinic?
No. Veins aren't treatable with medications, but they can be effectively treated with procedures called sclerotherapy.
What types of visit can I have?
Video visits are available in all 50 states and D.C. Message-only visits are available in 34 states. To see your visit options, first choose your state.
How does Amazon Clinic protect my health information?
Amazon Clinic protects your health information by strictly following the requirements of the Health Insurance Portability and Accountability Act (HIPAA). HIPAA governs what Amazon Clinic and your healthcare providers can do with your medical information, as well as your contact and payment information. Amazon Clinic doesn’t and will never sell your personal information. Learn more on our privacy page.