Period cramp relief from an online doctor or nurse practitioner. Request prescription for period pain, menstrual cramps pain relief medication, birth control pills. Upfront pricing. No appointment or insurance needed.
Period cramp relief from an online doctor or nurse practitioner. Request prescription for period pain, menstrual cramps pain relief medication, birth control pills. Upfront pricing. No appointment or insurance needed.
Women, ages 18-55
This is right for you if
Your sex assigned at birth was female
You’re experiencing pelvic pain that corresponds to a regular period cycle
You’re not pregnant or nursing

Did you know?

• Up to 91% of young women experience period pain, and 29% of them report that their pain is severe

• Only 11% of young women seek medical advice about their menstrual cramps

• Studies show that self-medication often leads to insufficient relief for period pain

What's included

Personalized period cramp relief plans may include prescriptions for medications that treat period pain (dysmenorrhea). Your online doctor or nurse practitioner may also recommend over-the-counter (OTC) menstrual cramp relief medications and self-care strategies. They won’t prescribe narcotic painkillers. You can message your clinician with follow-up questions for 14 days after you get your treatment plan.

If you need treatment for an additional health condition, you’ll need to start a separate visit.
Commonly prescribed period cramp medications
  • NuvaRing
  • Sprintec
  • Nonsteroidal anti-inflammatory agents (NSAIDs)
Compare clinics
This chart is for informational purposes only. Your clinician will determine treatment plans, prescriptions, and number of refills (if any) based on your symptoms and health history.
Period cramp relief isn’t available at Curai Health or SteadyMD at this time. Alpha and Wheel have licensed clinicians (like MDs, DOs, and NPs). At Alpha, the typical prescription is a 30-day supply and 11 refills. Alpha won’t prescribe diclofenac (Cataflam). At Wheel, the typical prescription is a 90-day supply and 3 refills. Wheel won’t prescribe mefenamic acid.

What you’ll need

A blood pressure reading from the past 12 months
Your height and weight
A photo ID, like a driver's license or passport, if we need additional identity verification
5 to 10 minutes to answer questions about your symptoms and health history

How it works

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Choose an online clinic
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Fill out an intake form
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Connect with a clinician, no appointment needed
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Get a personalized treatment plan
You can message your clinician with follow-up questions for 14 days after you get your treatment plan.
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You should know
Based on your health information, your clinician may recommend that you see a healthcare provider in person. If that happens, you won’t be charged for your visit. Amazon Clinic doesn’t accept insurance at this time, and isn’t intended for beneficiaries of government payor programs, including Medicare and Medicaid.

Frequently asked questions

What causes menstrual cramps?
Menstrual cramps are caused by painful contractions of the uterus. These contractions result in the release of the uterine lining once a month (a period). The uterus knows when it's time to start contracting when it gets a signal from prostaglandins.

Prostaglandins are compounds that function like hormones in the body. Studies show that higher prostaglandin levels can lead to more uterine cramps, higher uterine pressure, and more pain, while lower prostaglandin levels can lead to fewer uterine cramps, lower uterine pressure, and less pain.

Pharmacological approaches to period pain relief tend to focus on lowering prostaglandin levels. For example, prescription nonsteroidal anti-inflammatory drugs (NSAIDs) can bind to enzymes involved in prostaglandin synthesis. By inhibiting this enzyme activity, these drugs can reduce pain levels.
When should I be worried about pelvic pain?
When pelvic pain is caused solely by a menstrual cycle, it's called primary dysmenorrhea (painful menstruation). When pelvic pain has another underlying cause, like endometriosis or uterine fibroids, it's called secondary dysmenorrhea.

Primary dysmenorrhea

1. Pain cycles may begin 6 to 12 months after getting your first menstrual period

2. Pain may start 2 to 3 days before you get your period or when you start bleeding

3. Pain may last 8 to 72 hours

4. Pain may decrease as you get older

Secondary dysmenorrhea

1. Pain may be unusually severe and worse with time

2. Pain may last longer than 2 to 3 days

3. Pain may start later in life (like after age 25)

Clinicians usually recommend seeing a healthcare provider in person, likely for a pelvic exam, if you haven't experienced period pain relief after 3 to 6 months of NSAID or hormonal contraceptive treatment. They also recommend seeing a doctor if you have other symptoms of secondary dysmenorrhea, like pain during sex, pelvic pain that isn't related to your menstrual cycle, or abnormal bleeding.
What menstrual pain medications can I get through Amazon Clinic?
For menstrual pain relief, your clinician may prescribe a specialized NSAID or a hormonal contraceptive.

Specialized NSAIDs like mefanamic acid and diclofenac can help relieve period pain by blocking prostaglandin action. They can be more effective for treating menstrual cramps than over-the-counter NSAIDs like ibuprofen, which are derived from phenylpropionic acid.

Your clinician may also prescribe hormonal contraceptives, which can lower prostaglandin levels. Forms of birth control your clinician may prescribe include pills, a vaginal ring, a subcutaneous injection (Depo-Provera), or a patch.

Please note: This information is for general reference only. Your online doctor or nurse practitioner will review your symptoms and health history to determine which (if any) dysmenorrhea treatments are medically appropriate.
Can I get treatment through Amazon Clinic if I have endometriosis?
Symptoms of endometriosis, a chronic condition that affects 1 in 10 women of reproductive age, can be treated with many of the same therapies that treat period cramps. If you've already been diagnosed with endometriosis, you can seek relief from your symptoms through Amazon Clinic.

Endometriosis is caused by endometrium cells growing and forming lesions outside the uterus (ectopically). The condition can cause inflammation, intense pain, and sometimes infertility. If you have signs of secondary dysmenorrhea (see "Should I be worried about pelvic pain?"), then make an appointment with a trusted healthcare provider like an obstretrician-gynecologist (OB-GYN) to rule out endometriosis.

Endometriosis can be diagnosed with medical imaging (ultrasound or MRI) or a surgical biopsy, yet it often takes years (10 on average) for women to be diagnosed.
Are there any natural treatments for period pain relief?
Research has shown some benefits of exercise, applied heat (heating pads or hot water bottles), acupuncture, acupressure, and transcutaneous electrical nerve stimulation (TENS) on period pain.
What types of visit can I have?
Video visits are available in all 50 states and D.C. Message-only visits are available in 34 states. To see your visit options, first choose your state.
How does Amazon Clinic protect my health information?
Amazon Clinic protects your health information by strictly following the requirements of the Health Insurance Portability and Accountability Act (HIPAA). HIPAA governs what Amazon Clinic and your healthcare providers can do with your medical information, as well as your contact and payment information. Amazon Clinic doesn’t and will never sell your personal information. Learn more on our privacy page.
  1. Armour, M., Parry, K., Al-Dabbas, M. A., Curry, C., Holmes, K., MacMillan, F., Ferfolja, T., & Smith, C. A. (2019). Self-care strategies and sources of knowledge on menstruation in 12,526 young women with dysmenorrhea: A systematic review and meta-analysis. PloS one, 14(7), e0220103. Retrieved from
  2. Armour, M., Parry, K., Manohar, N., Holmes, K., Ferfolja, T., Curry, C., MacMillan, F., & Smith, C. A. (2019). The Prevalence and Academic Impact of Dysmenorrhea in 21,573 Young Women: A Systematic Review and Meta-Analysis. Journal of women's health (2002), 28(8), 1161–1171. Retrieved from
  3. Ju, H., Jones, M., & Mishra, G. (2014). The prevalence and risk factors of dysmenorrhea. Epidemiologic reviews, 36, 104–113. Retrieved from
  4. Nie, W., Xu, P., Hao, C., Chen, Y., Yin, Y., & Wang, L. (2020). Efficacy and safety of over-the-counter analgesics for primary dysmenorrhea: A network meta-analysis. Medicine, 99(19), e19881. Retrieved from
  5. Oladosu, F. A., Tu, F. F., & Hellman, K. M. (2018). Nonsteroidal antiinflammatory drug resistance in dysmenorrhea: epidemiology, causes, and treatment. American journal of obstetrics and gynecology, 218(4), 390–400. Retrieved from
  6. Sharghi, M., Mansurkhani, S. M., Larky, D. A., Kooti, W., Niksefat, M., Firoozbakht, M., Behzadifar, M., Azami, M., Servatyari, K., & Jouybari, L. (2019). An update and systematic review on the treatment of primary dysmenorrhea. JBRA assisted reproduction, 23(1), 51–57. Retrieved from